Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Symptom improvement
RCT	294 people with dyspeptic symptoms and confirmed H pylori infection	Proportion of people free of dyspeptic symptoms 1 year 41/145 (28%) with eradication treatment 22/149 (15%) with placebo	ARI 13% 95% CI 4% to 24% P = 0.008	Effect size not calculated	eradication treatment
RCT	184 people with H pylori infection and long-term proton pump inhibitor use	Mean change in dyspepsia symptom scores from baseline (measured by Leeds Dyspepsia Questionnaire, score range 0–40) 1 year –2.7 with eradication therapy +0.4 with placebo	Mean difference –3.1 95% CI –5.3 to –0.9 P = 0.005	Effect size not calculated	eradication treatment