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. 2009 Mar 10;2009:0321.
Ref (type) Population Outcome, Interventions Results and statistical analysis Effect size Favours
Return visit or re-admission to hospital

Systematic review
120 children aged 6 months to 14 years with stridor and chest wall retractions at rest and croup score 3 or greater (see table 1 )
Data from 1 RCT
Proportion of children requiring return visit or re-admission to hospital by 7–10 days
2/31 (6%) with single oral dexamethasone dose of 0.6 mg/kg
1/29 (3%) with single oral dexamethasone dose of 0.3 mg/kg

RR 1.87
95% CI 0.18 to 19.55
Not significant

Systematic review
120 children aged 6 months to 14 years with stridor and chest wall retractions at rest and croup score 3 or greater
Data from 1 RCT
Proportion of children requiring return visit or re-admission to hospital by 7–10 days
1/31 (3%) with single oral dexamethasone dose of 0.3 mg/kg
0/29 (0%) with single oral dexamethasone dose of 0.15 mg/kg

RR 2.81
95% CI 0.12 to 66.40
Not significant

RCT
3-armed trial
99 children aged 6 months to 6 years with Westley Croup Score greater than 2 (see table 1 ) Proportion of children re-presenting for additional medical attention for croup 1 week
4/30 (13%) with oral dexamethasone 0.15 mg/kg
3/27 (11%) with oral dexamethasone 0.6 mg/kg
5/29 (17%) with oral prednisolone 1 mg/kg

P = 0.86 for difference among the three groups
Significance of each dexamethasone group alone versus prednisolone alone not reported
Not significant
Hospital admission rates

RCT
3-armed trial
99 children aged 6 months to 6 years with Westley Croup Score greater than 2 (see table 1 ) Proportion of children admitted to hospital during the initial emergency department attendance
2/33 (6%) with oral dexamethasone 0.15 mg/kg
1/30 (3%) with oral dexamethasone 0.6 mg/kg
4/34 (12%) with oral prednisolone 1 mg/kg

P = 0.498 for difference among the three groups
Significance of each dexamethasone group alone versus prednisolone alone not reported
Not significant

RCT
72 children aged 6 months to 13 years with Westley Croup Score of 3–6 Proportion of children admitted to hospital after the initial clinic visit
14/36 (39%) with single oral dexamethasone dose of 0.15 mg/kg
15/36 (42%) with single oral dexamethasone dose of 0.6 mg/kg

P = 0.36
Not significant