Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Treatment failure rates
Systematic review	1519 people	Treatment failure rates 2 weeks 272/809 (34%) with allylamines 243/710 (34%) with azoles	RR 0.86 95% CI 0.70 to 1.06		Not significant
Systematic review	173 people	Treatment failure rates 6 weeks 21/102 (21%) with allylamines 40/71 (56%) with azoles	RR 0.34 95% CI 0.22 to 0.52	Moderate effect size	allylamines
Systematic review	83 people	Treatment failure rates 6 weeks 7/40 (18%) with terbinafine 21/43 (49%) with clotrimazole	RR 0.36 95% CI 0.17 to 0.75	Moderate effect size	terbinafine
Systematic review	962 people	Treatment failure rates 6 weeks 26/488 (5%) with allylamines 38/474 (8%) with azoles	RR 0.75 95% CI 0.33 to 1.72		Not significant
Systematic review	1003 people	Treatment failure rates 6 weeks 102/533 (19%) with allylamines 155/470 (33%) with azoles	RR 0.63 95% CI 0.42 to 0.94	Small effect size	allylamines
Systematic review	141 people	Treatment failure rates 12 weeks or above 8/75 (11%) with allylamines 16/66 (24%) with azoles	RR 0.47 95% CI 0.22 to 1.02		Not significant