Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Treatment failure rates
Systematic review	168 people	Treatment failure rates 2 weeks 18/85 (21%) with ciclopirox olamine 41/83 (49%) with placebo	RR 0.43 95% CI 0.27 to 0.68	Moderate effect size	ciclopirox olamine
Systematic review	461 people	Treatment failure rates 4 weeks 38/231 (16%) with ciclopirox olamine 164/230 (71%) with placebo	RR 0.27 95% CI 0.11 to 0.66	Moderate effect size	ciclopirox olamine
Mycological cure rates
RCT 3-armed trial	100 people with interdigital tinea pedis	Mycological cure rates 4 weeks 82% with ciclopirox olamine once daily 80% with ciclopirox olamine twice daily 43% with placebo Absolute numbers not reported	P = 0.007 for ciclopirox olamine once daily v placebo P = 0.013 for ciclopirox olamine twice daily v placebo