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. 2009 Jul 20;2009:1712.
Ref (type) Population Outcome, Interventions Results and statistical analysis Effect size Favours
Adverse effects

Systematic review
Unclear Serious adverse effects
with allylamines
with placebo
Absolute results not reported

Two RCTs included in the review reported an increase in liver enzymes with terbinafine cream 1% and with placebo, and one RCT reported neutropenia with placebo (results not reported). The adverse effects reported by RCTs in the review included burning, stinging, and itching sensations (further details not reported)

RCT
324 people with interdigital tinea pedis Adverse effects
with terbinafine
with placebo
Absolute results not reported

The RCT found no serious adverse effects associated with terbinafine 1% solution. Adverse effects reported included mild burning, moderate peripheral oedema, mild pain, and pruritus (further details not reported)

RCT
84 people Adverse effects
with terbinafine 1% or 3%
with placebo

The RCT found no serious adverse effects associated with terbinafine 1% and 3% emulsion gel. Adverse effects reported included burning and stinging sensations, mild desquamation, erythema, and incrustation dryness (further details not reported)