Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Delirium | |||||
RCT 3-armed trial |
30 people admitted to hospital with advanced AIDS In review |
Change in delirium from baseline (measured by Delirium Rating Scale; lower scores indicate better function)
2 days
12.08 with chlorpromazine at 2 days 20.62 with baseline Absolute results not reported |
No direct comparison between groups reported P <0.001 for change from baseline with chlorpromazine |
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RCT 3-armed trial |
30 people admitted to hospital with advanced AIDS In review |
Change in delirium with longer treatment (measured by Delirium Rating Scale; lower scores indicate better function)
between 2 and 7 days
12.08 with chlorpromazine at 2 days 11.85 with chlorpromazine at 7 days Absolute results not reported |
No direct comparison between groups reported P <0.06 for change between 2 and 7 days with chlorpromazine |
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RCT 3-armed trial |
30 people admitted to hospital with advanced AIDS In review |
Cognition measured by the Mini- Mental State Examination: higher scores indicate better function
2 days
13.45 with chlorpromazine 10.92 with baseline Absolute results not reported |
No direct comparison between groups reported P <0.001 for change from baseline with chlorpromazine |