Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Adverse effects | |||||
Systematic review 3-armed trial |
30 people admitted to hospital with advanced AIDS Data from 1 RCT |
Extrapyramidal adverse effects
with haloperidol |
The review assessed adverse effects using the Extrapyramidal Symptom Rating Scale, because of consensus that extrapyramidal effects are likely to be seen with neuroleptic drugs acting on dopaminergic receptors. No participants taking haloperidol developed dyskinetic or dystonic symptoms, and there was no increase in parkinsonism |