Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Wart clearance
Systematic review	313 people 3 RCTs in this analysis	Proportion of people with wart clearance 3 to 8 months 77/158 (49%) with 2-week interval between cryotherapy treatments 70/155 (45%) with 3-week interval between cryotherapy treatments	RR 1.03 95% CI 0.77 to 1.37		Not significant
Systematic review	161 people 2 RCTs in this analysis	Proportion of people with wart clearance 3 to 6 months 50/77 (65%) with 3-week interval between cryotherapy treatments 41/84 (49%) with 4-week interval between cryotherapy treatments	RR 1.42 95% CI 0.76 to 2.63		Not significant
Systematic review	167 people 2 RCTs in this analysis	Proportion of people with wart clearance 3 to 6 months 49/83 (59%) with 2-week interval between cryotherapy treatments 41/84 (49%) with 4-week interval between cryotherapy treatments	RR 1.29 95% CI 0.70 to 2.38		Not significant