Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
RCT	37 people aged 19 to 70 years	Incidence of crust and purpura 11% with pulsed dye laser at 595 nm (spot size 5 mm, impulse duration 0.45 ms, flux 9 J/cm2 with 5 passes at a frequency of 1 Hz) 0% with placebo Absolute numbers not reported	Significance not assessed
RCT	37 people aged 19 to 70 years	Pain levels (measured on a 10-point visual analogue scale) 4.7 with pulsed dye laser at 595 nm (spot size 5 mm, impulse duration 0.45 ms, flux 9 J/cm2 with 5 passes at a frequency of 1 Hz) 1.5 with placebo	Significance not assessed
RCT	37 people aged 19 to 70 years	Tolerance (measured on a 10-point visual analogue scale) 8.31 with pulsed dye laser at 595 nm (spot size 5 mm, impulse duration 0.45 ms, flux 9 J/cm2 with 5 passes at a frequency of 1 Hz) 9.81 with placebo	Significance not assessed