Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Vomiting
RCT	51 people with advanced cancer with chronic nausea caused by the disease or by chemotherapy or radiotherapy	Mean nausea intensity at 3 days on a scale of 0–10 where 0 = symptom absent and 10 = worst possible symptom 4.5 with dexamethasone plus metoclopramide 2.9 with placebo plus metoclopramide	P = 0.16 Note: although no significant difference between groups, nausea improved in both groups from baseline		Not significant
RCT	51 people with advanced cancer with chronic nausea caused by the disease or by chemotherapy or radiotherapy	Mean nausea intensity at 8 days on a scale of 0–10 where 0 = symptom absent and 10 = worst possible symptom 5.9 with dexamethasone plus metoclopramide 5.7 with placebo plus metoclopramide	P = 0.85 Note: although no significant difference between groups, nausea improved in both groups from baseline		Not significant
RCT	51 people with advanced cancer with chronic nausea caused by the disease or by chemotherapy or radiotherapy	Vomiting with dexamethasone plus metoclopramide with placebo plus metoclopramide Absolute results not reported	Reported as not significant P value not reported Note: although no significant difference between groups, nausea improved in both groups from baseline		Not significant