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. 2010 May 18;3(5):1576–1593. doi: 10.3390/ph3051576

Table 3.

Kinase inhibitors that directly and indirectly target Mdm2, Mdmx and p53.

Kinase Inhibitor
c-Abl imatiniba [66], dasatiniba,b [67,68], nilotiniba,b [69], ON012380c [70]
ATM KU-55933a [71], KU-60019a [72], CP466722 [73]
CDK SNS-032 [74], AT7519a [75]
Chk1/Chk2 AZD7762a [76]
CSN curcumin
DNA-PK morphlins [77], NU-7441a [78], NU-7422a [79], LY294002a [80].
ERK lapatiniba [81]
JNK SP600125a [82]
MAPKAP2 pyrazinoindolone [83], subersic acid [84], makassaric acid [84]
PKC ingenol 3-angelatec [85,86], midostaurina [87], safingol [88]
TAF1 apigenina [89]

a Type I inhibitors; b Type II inhibitors; c allosteric inhibitors; d irreversible covalent inhibitors.