Table 1.
Cell-adhesive peptides (CAPs) that have been used for cell-adhesive modification of PEG hydrogels.
| CAP | Origin a | Cell receptor | Monomer type | Ref. |
|---|---|---|---|---|
| RGD | FN, LN, Collagen | Integrins | Monoacrylate | 7,134–146 |
| Diacrylate | 147,148 | |||
| Monothiol | 21,149–154 | |||
| Monoazide | 155 | |||
| Diazide | 155 | |||
| Monomaleimide | 23 | |||
| Mono-QAP b | 26 | |||
| KQAGDV | FN | Integrin | Monoacrylate | 138–141,145 |
| REDV | FN | Integrin α4β1 | Monoacrylate | 118 |
| PHSRN | FN | Integrin α5β1 | Monoacrylate | 142,143 |
| Monothiol | 150 | |||
| IKVAV | LN α1 | 110 kDa protein | Monoacrylate | 144,146 |
| Monothiol | 151 | |||
| Monobiotin | 124 | |||
| YIGSR | LN | 67 kDa protein | Monoacrylate | 144–146 |
| Monothiol | 150 | |||
| PDGSR | LN | Integrin | Monoacrylate | 144,146 |
| LRGDN | LN | Integrin | Monoacrylate | 146 |
| LRE | LN | Integrin | Monoacrylate | 144 |
| IKLLI | LN | Heparin | Monoacrylate | 144,146 |
| GFOGER | Collagen-I | Integrin α2β1 | Monoacrylate | 141 |
| VAPG | Elastin | 67 kDa protein | Monoacrylate | 139,140,145,156 |
FN, fibronectin; LN, laminin.
QAP, Gln acceptor peptide (NQEQVSPL).