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. Author manuscript; available in PMC: 2010 Jul 21.
Published in final edited form as: Neuropsychopharmacology. 2007 Dec 12;33(10):2341–2351. doi: 10.1038/sj.npp.1301649

Figure 4.

Figure 4

Increased indoleamine 2,3-dioxygenase (IDO) mRNA expression in brain of aged mice after peripheral lipopolysaccharide (LPS) injection. Young adult and aged mice were injected i.p. with either saline or LPS and IDO mRNA was measured by real-time RT–PCR in whole brain collected at (a) 4 or (b) 24 h later. Bars represent the mean ± SEM (n = 6). Means with (*) are significantly different (P < 0.05).