Table 1.

Baseline demographic, clinical and biochemical data for 70 women with the polycystic ovary syndrome, stratified by the presence or absence of the metabolic syndrome.

	No MBS (n=46)	MBS (n=24)	P-value	All
Age (years)	29.1 ± 10.5	32.6 ± 11.5	0.2052	30.3 ± 10.9
Race			0.4822
Caucasian	43 (93.5%)	21 (87.5%)		64 (91.4%)
AA	2 (2.8%)	1 (4.2%)		3 (4.3%)
Other	1 (1.4%)	2 (8.3%)		3 (4.3%)
Length of follow up (months)	34.8 ± 21.5	38.4 ± 25.7	0.6966	36.1 ± 22.9
Final metformin dose (mg)	1932.6±222.2	1958.3 ± 204.1	0.6381	1941.4±215
Positive Family History of Diabetes	17 (37.0%)	10 (41.7%)	0.3902	27 (38.6%)
Weight (kg)	80.5 ± 17.7	105.9 ± 21.0	<.0001	89.2 ± 22.4
BMI (kg/m2)	29.2 ± 6.1	38.5 ± 7.0	<.0001	32.4 ± 7.8
Systolic Blood Pressure (mmHg)	114.6 ± 11.6	125.8 ± 12.2	0.0005	118.5 ± 12.9
Diastolic Blood Pressure (mmHg)	72.5 ± 7.9	80.8 ± 11.0	0.0004	75.4 ± 9.8
Total Testosterone (ng/dL)	51.6 ± 18.1	66.0 ± 20.3	0.0039	56.5 ± 19.9
Free Testosterone (ng/dL)	1.01 ± 0.51	1.31 ± 0.60	0.0399	1.11 ± 0.56
Total Cholesterol (mg/dL)	185.3 ± 38.0	206.8 ± 39.2	0.0292	192.7 ± 39.5
LDL-C (mg/dL)	111.2 ± 31.3	122.4 ± 28.6	0.0308	115.1 ± 30.7
HDL-C (mg/dL)	52.0 ± 11.9	44.2 ± 9.2	0.0067	49.3 ± 11.6
Triglycerides (mg/dL)	108.5 ± 88.9	203.2 ± 86.4	<0.0001	141.0 ± 98.5
Fasting Glucose (mg/dL)	82.5 ± 7.5	88.1 ± 10.0	0.0249	84.4 ± 8.8
Sex Hormone Binding Globulin‡(μg/mL)	3.38 [2.63–4.34]	4.78 [3.35–6.80]	0.1863	3.80 [3.08–4.68]
Concurrent Oral Contraceptives	6 (13.0%)	5 (20.8%)	0.4031	11 (15.71%)
Concurrent Spironolactone	11 (23.9%)	3 (12.5%)	0.2428	14 (20.0%)

MBS=Metabolic syndrome

p-value is for comparison between women with and without MBS at baseline

Values are presented as mean ± SD, or number (%) except where noted

^‡Geometric mean with 95% confidence intervals