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. 2010 Jul 2;3:12. doi: 10.1186/1755-8166-3-12

Figure 2.

Figure 2

Characterization of the t(2;22) by molecular cytogenetic techniques. A) Partial multicolor karyotype showing normal chromosome 2, normal chromosome 22 and both derivative chromosomes resulting from t(2;22)(q?36;q?12). B) Metaphase FISH with EWSR1 break-apart probe. An intact dual-color EWSR1 signal can be seen on normal chromosome 22, a green signal on the der(2) and a red signal on the der(22). C) Interphase FISH with the CREB1 break-apart probe showing break-apart signals (1 fused, 1 green and 1 red signals).