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. 2010 Jun 22;11:130. doi: 10.1186/1471-2474-11-130

Table 7.

Median Percent Changes From Baseline in Selected Lipid Parameters at Month 36a

Bazedoxifene Raloxifene Placebo
Parameter 20 mg 40 mg 60 mg
Total cholesterol
No. of pairs 1220 1201 1225 1248
Median percent change -3.8b,c,d -3.5b,c,d -5.0b,c 0.3
LDL cholesterol
No. of pairs 1220 1201 1223 1247
Median percent change -5.4b,c,d -6.6b,c,d -8.5b,c 1.6b
HDL cholesterol
No. of pairs 1216 1196 1219 1246
Median percent change 5.1b,c 5.9b,c 5.0b,c 2.5b
LDL/HDL cholesterol
No. of pairs 1213 1191 1215 1244
Median percent change -10.5b,c,d -12.6b,c -12.4b,c -0.6
Triglycerides
No. of pairs 1220 1201 1225 1248
Median percent change 8.5b 13.6b 12.2b 12.1b

LDL, low-density lipoprotein; HDL, high-density lipoprotein.

aIncludes subjects in the intent-to-treat population (n = 6,847) with an assessment at baseline and at Month 36.

bP < 0.001 vs baseline; t test.

cP < 0.001 vs placebo; t test.

dP < 0.01 vs raloxifene 60 mg; t test.