Table 5.
Meta-analyses of association between p53 mutations, p16 and HPV
| Before outlier exclusion | After outlier exclusion | ||||
|---|---|---|---|---|---|
| Outcome | Marker | No. of Studies | Adjusted OR (95% CI) | No. of Studies | Adjusted OR (95% CI) |
| HPV positive | p53 (mutated) | 4 | 0.21(0.04-0.38) | 4 | 0.21(0.04-0.38) |
| P = 0.015 | |||||
| HPV positive | p16 | 2 | 5.02(1.08-8.97) | 1 | 3.00(0.90-9.70) |
| IHC | p = 0.181 | ||||