TABLE 1.

Base-case probability and cost estimates and their ranges for sensitivity analysis

	Base-case estimate (min/max)	References
Probabilities
Metastasis prevalence	0.30 (0.15/0.45)	2,3
Ultrasound sensitivity	0.63 (0.26/0.92)	5,7
Ultrasound specificity	0.91 (0.44/0.98)	5,7
FNA sensitivity	0.65 (0.06/0.95)	5,7
FNA specificity	0.99 (0.90/1.00)	5,7
SLN surgery sensitivity	0.93 (0.77/0.98)	6,8–12
SLN surgery specificity	0.99 (0.90/1.00)	6,8–12
Costs
SLN surgery	$10,078 ($6,522/$17,473)	Patient data
ALND	$11,045 ($7,250/$19,315)	Patient data
SLN surgery and ALND	$13,321 ($8,402/$23,537)	Patient data
FNA with imaging guidance	$128 ($64/$512)	Medicare reimbursement
Ultrasound of breast	$98 ($49/$392)	Medicare reimbursement
Echo guidance for biopsy	$206 ($103/$824)	Medicare reimbursement
Cytopathology evaluation for FNA	$142 ($71/$568)	Medicare reimbursement

ALND axillary lymph node dissection, FNA fine-needle aspiration, SLN sentinel lymph node