Table 1.

Genetic diversity in the gene encoding apical membrane antigen-1 (AMA1) before and after immunization with a bivalent AMA1 malaria vaccine

	Number of sequences	Number of haplotypes	Haplotype diversity (Hd)	Nucleotide diversity (π)	Average number of nucleotide differences (k)	Tajima D	Tajima D p-value
Control group
Baseline	23	22	0.996	0.0163	19.672	0.3308	> 0.1
Post-immunization	129	96	0.993	0.0172	20.729	1.4110	> 0.1
Control total	152	112	0.994	0.0179	20.726	0.9110	> 0.1
AMA1 vaccine group
Baseline	21	21	1.000	0.0176	21.210	0.2413	> 0.1
Post-immunization	142	94	0.989	0.0172	20.773	1.8010	> 0.05
AMA1 vaccine total	163	106	0.990	0.0172	20.792	1.0150	> 0.1