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. 2010 Jul 21;5(7):e11644. doi: 10.1371/journal.pone.0011644

Table 2. IC50 values of biologically active oligosaccharides and FGFR and EGFR-2 inhibitors in endothelial cell migration assay.

Oligosaccharide/RTKi FGF2 VEGF165
µg/ml µM µg/ml µM
8-mer 2SNS 2.86 1.2 ND ND
9-mer 2SNS 2.11 0.83 9.17 3.6
10-mer 2SNS 0.30 0.1 3.54 1.2
12-mer 2SNS 0.38 0.11 0.58 0.17
PD173074 - 0.082 ND ND
SU4312 ND ND - 0.19

The mean of at least two independent experiments is represented. No more than 2-fold differences between IC50s in two independent experiments were observed. ND - not determined; RTKi – receptor tyrosine kinase inhibitor.