Table 2. Serum/plasma concentrations of homocysteine, folate, PLP, vitamin B12 and BMI, by quartiles of blood Pb in Pakistani adults.
Blood Pb | |||||
Characteristics* | Q1 (n = 218) | Q2 (n = 218) | Q3 (n = 218) | Q4 (n = 218) | p value** |
Homocysteine, µmol/L | 13.3 (9.7)/11.1(8.6–14.3) | 14.6 (7.5)/12.7 (9.9–16.7) | 15.2 (9.1)/12.5 (9.9–17.0) | 16.1 (11.2)/13.1 (10.3–17.8) | 0.017 |
Folate, ng/mL | 6.9 (4.8)/5.6 (3.3–9.1) | 6.8 (4.4)/5.9 (3.7–8.8) | 6.3 (4.4)/5.0 (3.2–8.0) | 6.4 (4.3)/5.3 (3.3–8.6) | 0.3 |
PLP, nmol/L | 34.9 (33)/28.6 (16.4–41.0) | 32.2 (30.6)/25.1 (18.0–37.1) | 31.9 (29.9)/26.5 (18.0–35.6) | 33.4 (36.5)/25.6 (17.4–35.0) | 0.7 |
Vitamin-B12, pg/mL | 442 (230)/397 (300–532) | 424 (223)/400 (270–540) | 434 (232)/385 (280–532) | 462 (231)/430 (313–565) | 0.3 |
BMI, kg/m2 | 25.6 (5.8)/25.3 (21.1–29.1) | 24.6 (5.3)/23.9 (20.5–28.1) | 24 (5.5)/22.8 (20.0–28.1) | 23.4 (5.9)/22.5 (19.1–26.8) | 0.001 |
*Values are expressed as mean (SD)/median (IQR).
**p value is obtained by comparing mean (SD) values in four blood Pb quartiles by using one way ANOVA followed by Bonferroni test.
BMI = body mass index.
PLP = pyridoxal phosphate.