Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Population pharmacokinetic parameters of indinavir for the basic and the final model: estimates and relative standard error (RSE)
| Parameters | Basic model (N = 40) | Covariate model (N = 38) | |||
|---|---|---|---|---|---|
| Estimates | RSE (%) | Estimates | RSE (%) | ||
| ka(h−1) | 1.3 | 33.7 | 2.1 | 44.1 | |
| - | - | −1.3 | 42.0 | ||
| Cl/F (L/h) | 21.9 | 6.9 | 22.2 | 6.9 | |
| V/F (L) | 93.9 | 8.2 | 97.3 | 9.3 | |
| ωka (%) | 118.0 | 22.9 | 98.2 | 28.7 | |
| ωCl/F (%) | 34.4 | 15.0 | 34.9 | 15.0 | |
| ωV/F (%) | 19.3 | 66.8 | 21.6 | 57.8 | |
| σ (%) | 44.5 | 8.9 | 44.7 | 8.6 | |
RSE = relative standard error
