Fig. 2. TS1×HACII mice develop spontaneous autoimmune inflammatory arthritis.
(A) Pictures show 20-week-old TS1 and TS1×HACII littermates, with panels showing front and rear paws. (B) Graph shows ankle widths of TS1 and TS1×HACII mice at different ages, in weeks. **P≤0.01. (C) Hematoxylin and eosin (H&E) stained knee sections from 23-week-old TS1 and TS1×HACII littermates; b, bone; c, cartilage; s, synovium; p, pannus; arrowhead, bone erosion.
