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. Author manuscript; available in PMC: 2010 Jul 22.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3620–3628. doi: 10.1167/iovs.04-0258

Figure 3.

Figure 3

Representative dynamic photorefraction-measured accommodative responses before and after subconjunctival injection of (A) 2% pirenzepine and (B) saline in monkey 38. Each trace is the average of three responses recorded from 4-second stimuli, delivered every 2 minutes for 30 minutes after pirenzepine or saline injection. The time scale on the graph is in minutes, but the individual accommodative responses, lasting only 4 seconds each, are scaled so the individual responses can be seen. (C) After 2% pirenzepine injection, mean normalized photorefraction-measured accommodative response amplitude in response to a single, maximum stimulus current amplitude delivered every 2 minutes decreased to approximately 10% of the pre-pirenzepine amplitude. Accommodative amplitude in response to a maximum stimulus current amplitude did not change over 20 minutes after subconjunctival injection of saline in the control monkey. Error bars, SEM.