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(A) After subconjunctival injection of 0.0002% to 2% pirenzepine, accommodation to a maximum current stimulus amplitude was measured every 2 minutes up to 40 minutes. Error bars, SEM. (B) Centrally stimulated accommodation to a maximum stimulus current amplitude was significantly decreased 20 to 40 minutes after subconjunctival injection of 0.02% pirenzepine or greater (paired t-test, *P < 0.05).
