Table 3.

Clinical and Neuropathological Correlations in Alzheimer’s disease

	Leg movement	Amount of leg movement	Hypersomnolence	Sleep difficulties	Hypocretin (Cytosolic)	Hypocretin (Membrane)	Alpha-synuclein (Cytosolic)	Alpha-synuclein (Membrane)
Leg movements	1.000	0.964(**)	−0.030	0.489(*)	0.396	0.424	−0.123	0.232
Amount of leg movements	0.964(**)	1.000	0.055	0.514(*)	0.355	0.512(*)	−0.137	0.250
Hypersomnolence	−0.030	0.055	1.000	0.161	0.190	0.158	−0.136	0.219
Sleep difficulties	0.489(*)	0.514(*)	0.161	1.000	0.485	0.515(*)	−0.408	−0.019
Hypocretin (Cytosolic)	0.396	0.355	0.190	0.485	1.000	0.252	−0.571(*)	−0317
Hypocretin (Membrane)	0.424	0.512(*)	0.158	0.515(*)	0.252	1.000	−0.309	−0.057
Alpha-synuclein (Cytosolic)	−0.123	−0.137	−0.136	−0.408	−0.571(*)	−0.309	1.000	0.587(*)
Alpha-synuclein (Membrane)	0.232	0.250	0.219	−0.019	−0.317	−0.057	0.587(*)	1.000

Results are presented as just Spearman’s rank correlation coefficients or Spearman’s rank correlation coefficient (significance indicator)

^**indicates significance at the 0.01 level (2-tailed) and

^*indicates significance at the 0.05 level (2-tailed).

Significant results are presented in bold type.