Fig. 8.

NKT cells participate in the afferent and efferent arms of AC. CD4⁺ T cells isolated from SRW-sensitized BALB/c donors were adoptively transferred into naive recipients. (A) Clinical scores of AC in naive WT recipients that received CD4⁺ T cells from either Jα18^−/− donors (closed inverted triangle) or WT donors (closed circle) that were sensitized with SRW pollen. (B) Eosinophilic infiltration into the conjunctivae of WT recipients of CD4⁺ T cells from SRW-sensitized Jα18^−/− or WT donors. (C) Clinical scores of AC in naive WT (closed circle) or Jα18^−/− (open circle) recipients of CD4⁺ T cells from WT donors that were sensitized with SRW pollen. (D) Eosinophilic infiltration into the conjunctivae of Jα18^−/− and WT BALB/c mice that received CD4⁺ T cells from WT BALB/c mice that were sensitized with SRW pollen. (n = 10) This graph is representative of two independent experiments; *P < 0.05.