FIG 1.
Heterozygous mutations may lead to reduced ligand binding. B cells (EBV cell lines) of subjects with TACI mutations indicated were tested to determine the binding of APRIL in comparison with the controls indicated. The mean fluorescence intensity (MFI, x-axis) for B cells (cell counts, y-axis) is shown. Isotype controls are marked in closed areas, surface APRIL fluorescence in open areas. NL, Normal.