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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2009 Dec;18(12):3389–3398. doi: 10.1158/1055-9965.EPI-09-0936

Figure 2.

Figure 2

Smoothing spline representation of the dose response curve for total intensity-years in adults from all sources. The curve represents the logit of relative risk as a function of dose, was calculated using a binomial Generalized Additive Model, and arbitrarily translated so that the logit corresponding to the lowest exposure is zero. The subjects are restricted to those with a Intensity-years score from all sources exceeding 4. The shaded area represents the point wise 95% confidence interval, and the dotted line shows response of zero.