Figure 1. Macrophages and IL-1β counteract TRAIL-induced inhibition of colon cancer growth.

A and B: HCT116 and Hke-3 cells were seeded at a density of 200 cells per well of a six well plate in the absence or the presence of macrophages (1600/well) or IL-1β, and were treated with TRAIL for 4 hours. The results shown in B represent the average of two independent experiments each performed in duplicate.