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. 2010 Jul 22;5(7):e11700. doi: 10.1371/journal.pone.0011700

Figure 4. Pharmacological inhibition of IL-1β secretion by Vitamin D3 inhibits the prosurvival function of macrophages.

Figure 4

A: The amount of apoptosis was determined in HCT116 cells treated with TRAIL under indicated conditions. Error bars were derived from 2 independent experiments. B: The effect of vitamin D3 on TRAIL-induced activation of caspases and the cleavage of PARP and β-catenin was determined by immunoblotting.