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. 2010 Jun 28;8:39. doi: 10.1186/1741-7015-8-39

Table 3.

Quality assessment of trials included in the meta-analysis

Trial ID Total score Blinding Outcome measure: blood pressure Loss to follow-up Funding source Compliance; other chocolate diary
Scores given 1: choc + control blinded 1: Primary 1: < 20% 1: Sponsor not involved in data collection, analysis 1: Compl assessed; no sign diff between groups
0.5: control blinded 0.5: Secondary 0: ≥ 20% 0: Sponsor involved 1: Compl assessed, sign diff included in analysis
0: No blinding 0: Compl not assessed
Taubert et al. [10] 4 0: dark/white 1 1: none 1 1
Murphy et al. [15] 3.5 1: cocoa tablets 0.5 1: 9.5% (4 of 42) 0: supported by Mars 1: tablet count, 7 day weight food records x2
Engler et al. [11] 5 1: flav bar matched 1 1: none 1 1
Fraga et al. [12] 2.5 0: dark/white 1 1: 3.6% (1 of 28) 0: 3 authors from Mars 0.5: reported what consumed, no diary
Grassi et al. [13] 3.5 0: dark/white 1 1: none 0.5: unclear 1: daily diary
Grassi et al. [13] 3.5 0: dark/white 1 1: none 0.5: unclear 1: daily diary
Taubert et al. [16] 4 0: dark/white 1 1: none 1 1: food diary
Crews et al. [17] 2.5 0.5: flav drink; > 50% assumed correct group they were in 1 0.5: 11% (11 of 101) 0.5: independent industry research grant, supplier 0: not reported
Grassi et al. [18] 3.5 0: dark/white 1 1: none 0.5: unclear 1: diary
Muniyappa et al. [20] 3 1: flav drink; blinding assessed ok 1 0: 31% (9 of 29) 1 0: not reported
Davison et al. [21] 3 1: flav drink 1 0: 21% (14 of 65) 0: Mars Financial support 1: diet + background exercise
Davison et al. [21] 3 1: flav drink 1 0: 21% (14 of 65) 0: Mars Financial support 1: diet + background exercise
Shiina et al. [22] 2 0: dark/white 0 1: none 1 0
Ried et al. [23] 4.5 0.5: control blinded 1 1: 8% (3 of 39) 1 1: diary
Monagas et al. [24] 3.5 0: cocoa powder in milk/milk 0.5 1: none 1 1: diet monitoring (3-day food questionnaires x3)

All 15 trial arms were adequately randomised.

Choc, chocolate; compl, compliance; flav, flavanol; sign diff, significant difference;