Table 3.
Summary of effect of lower age at menarche on 15-year survival
| Complete case analyses (n = 942) | Multiple imputation analyses (n = 1,031) | |||||
|---|---|---|---|---|---|---|
| Model | HR | 95% CI | P-value | HR | 95% CI | P-value |
| 1: Age adjusted | ||||||
| Menarche ≥ 12y | 1.00 | 1.00 | ||||
| Menarche < 12y | 1.35 | 1.05 - 1.73 | 0.018 | 1.30 | 1.02 - 1.65 | 0.032 |
| 2: Age + Health adjusteda | ||||||
| Menarche ≥ 12y | 1.00 | 1.00 | ||||
| Menarche < 12y | 1.31 | 1.02 - 1.68 | 0.037 | 1.26 | 0.98 - 1.61 | 0.070 |
| 3: Age + Health + Lifestyle adjustedb | ||||||
| Menarche ≥ 12y | 1.00 | 1.00 | ||||
| Menarche < 12y | 1.31 | 1.02 - 1.69 | 0.035 | 1.29 | 1.01 - 1.64 | 0.045 |
| 4: Age + Health + Lifestyle + Reproductive adjustedc | ||||||
| Menarche ≥ 12y | 1.00 | 1.00 | ||||
| Menarche < 12y | 1.28 | 0.99 - 1.65 | 0.062 | 1.25 | 0.98 - 1.60 | 0.074 |
a: Overall analyses adjusted for age group, place of residence, and health variables (self-rated health, cognitive function, number of morbid conditions).
b: Overall analyses adjusted for age group, place of residence, health variables, and lifestyle variables (smoking status, exercise status, BMI category).
c: Overall analyses adjusted for age group, place of residence, health variables, lifestyle variables, and reproductive variables (parity, age at menopause, number of reproductive years)