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. 2010 Jul 13;9:188. doi: 10.1186/1476-4598-9-188

Figure 2.

Figure 2

ALK expression is associated with ALK fusion status. (A) ALK is overexpressed at the mRNA level in 10 fusion-positive cases analyzed using Affymetrix Genechip® U133 plus 2.0. AP, Adjacent normal tissues; N, Cancer samples with no fusion; Y, Cancer samples positive for fusion. (B) ALK is differentially expressed between EML-ALK fusion-positive and negative samples (normalized intensity of 21.99 vs. 0.45, respectively; P = 0.0018), but EML4 expression was not significantly different between the groups. Error bars indicate mean ± standard deviation.