Table 2.
Serum bone metabolic markers over the study period for spring water and magnesium bicarbonate (supplemented) spring water groups
| Spring Water (n = 33) | Supplemented Spring Water (n = 34) | ||||
|---|---|---|---|---|---|
| Visit | Day 0 | Day 84 | Day 0 | Day 84 | |
| Parathyroid Hormone (pmol/L) | Mean (SD) | 3.85 (1.79) | 4.57 (2.14) | 4.24 (1.74) | 4.21 (1.96) |
| Change from baseline (Day 0) (SD) | 0.72 (1.52) | -0.02 (1.65) | |||
| *P value | 0.369 | 0.059 | |||
| 1,25dihydroxyvitamin D (pmol/L) | Mean (SD) | 120.8 (40.9) | 126.8 (40.4) | 118.7 (39.8) | 124.3 (40.7) |
| Change from baseline (Day 0) (SD) | 7.1 (49.1) | 5.6 (47.9) | |||
| *P value | 0.835 | 0.766 | |||
| Osteocalcin | Mean (SD) | 13.73 (5.44) | 14.42 (5.88) | 15.23 (3.89) | 13.79 (3.48) |
| (μg/L) | Change from baseline (Day 0) (SD) | 0.70 (4.00) | 0.07 (4.00) | -1.31 (3.89) | |
| *P value | 0.207 | 0.104 | |||
| N-telopeptide excretion | Mean (SD) | 36.7 (21.7) | 40.1 (21.3) | 34.1 (17.8) | 35.1 (15.7) |
| nmol/mM Cr) | Change from baseline (Day 0) (SD) | 3.4 (12.66) | 1.0 (15.97) | ||
| *P value | 0.588 | 0.440 | |||
| OH proline excretion (nmol/mM Cr) | Mean (SD) | 15.5 (5.39) | 17.2 (6.75) | 15.5 (4.98) | 15.6 (4.57) |
| Change from baseline (Day 0) (SD) | 1.6 (5.98) | 0.1 (4.70) | |||
| *P value | 0.971 | 0.216 | |||
*p-value comparing groups at Day 0 (italics) and for change from Day 0 to Day 84