Table 2.

The Evolutionary Rates (Ka, Ks, and the Ka/Ks ratio) of the Human–Chimpanzee and Human–Macaque 1:1 Orthologous Gene Pairs in H=C=M and non-H=C=M families.

	Human vs. Chimpanzee (median value)			Human vs. Macaque (median value)
Types of Gene Families	Ka	Ks	Ka/Ks	Ka	Ks	Ka/Ks
H=C=M	0.0027	0.0108	0.2516	0.0140	0.0662	0.2093
Non-H=C=M	0.0030	0.0119	0.2715	0.0169	0.0762	0.2301
P valuea	<10−4	<10−6	<0.05	<10−11	<10−15	<0.001

^aP values were estimated by using the two-tailed Wilcoxon rank sum test.