Figure 3.

Effect of azithromycin on GCF IL-8 and TNF-α content. Arrows indicate the times azithromycin was administered. Data represent the mean (± SEM) recovery in samples obtained from 12 separate maxillary interproximal sites. The treatment effects on IL-8 and TNF-α content were significant (P < 0.005, Friedman repeated-measures ANOVA on ranks). Significant differences from baseline IL-8 content are denoted by #, and significant differences from baseline TNF-α content are denoted by * (P < 0.05, Dunn’s test).