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. 2010 Aug;2(8):a003186. doi: 10.1101/cshperspect.a003186

Figure 3.

Figure 3.

Deregulation of FGF ligands and receptors in mammary cancer. MMTV proviral insertional mutagenesis led to the identification of five FGF ligands and the FGFR2 whose expression promoted mammary cancer. Some of these ligands have also been implicated in human breast cancer. FGFR1 and FGFR2 have also been shown to contribute to breast cancer development, whereas FGFR4 has been implicated in therapy response. The references used for this figure are: (1) (Theodorou et al. 2007), (2) (Peters et al. 1989), (3) (Theodorou et al. 2004), (4) (MacArthur et al. 1995), (5) (Naidu et al. 2001), (6) (Fioravanti et al. 1997), (7) (Berns et al. 1995), (8) (Jacquemier et al. 1998), (9) (Bansal et al. 1997), (10) (Zammit et al. 2002), (11) (Marsh et al. 1999), (12) (Adnane et al. 1991), (13) (Ray et al. 2004), (14) (Reis-Filho et al. 2006), (15) (Hunter et al. 2007), (16) (Easton et al. 2007), (17) (Meijer et al. 2008), (18) (Bange et al. 2002).