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Involvement of E2F-1, Apaf-1, and caspase-9 in PEA-induced apoptosis. YD-9 cells were cultured in the presence of 15 nM PEA for the indicated time, and whole cell lysates were subjected to Western blot analysis of E2F-1 (56 kDa), Apaf-1 (130 kDa), and caspase-9 (full-length, 49 kDa; cleaved, 37 kDa).
