. Author manuscript; available in PMC: 2011 Mar 20.

Published in final edited form as: Tetrahedron. 2010 Mar 20;66(12):2175–2180. doi: 10.1016/j.tet.2010.01.053

Table II.

Initial rates and enantioselectivities for the product formation in the transesterification reaction of different sec-alcohols with vinyl butyrate for subtilisin Carlsberg co-lyophilized with MβCD

Substrates	V_S^a	V_R^a	E^b	Substrates	V_S^a	V_R^a	E^b
First Group				Second Group
	177	59	3		255	28	9
	246	12	20		139	1.9	73
	102	2.3	44		59	0.4	141
	99	1.7	58		209	2.6	80
	183	2.7	67
Third Group				Fourth Group
	139	1.9	73		74	1.4	51
	228	2.2	104		49	24.5	2
	14	0.1	126^c
	32	0.1	240^c

Initial rates for the S- and R-enantiomer in nmol mg⁻¹min⁻¹

Measured by the ratio of [k_cat/K_M]_S/[k_cat/K_M]_R = V_S[R]/V_R[S]

Enantioselectivity could not be determined accurately because of the very low value of V_R