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Observed changes in Ih activation were attributable to PKA-independent effects of cAMP. A, Activation curves for Ih measured repeatedly in the absence of DA, but with the same experimental time course (n = 4). B, Ih activation curves in control and in the presence of forskolin and IBMX (n = 3). C, Ih activation curves in control and in H89 plus DA (n = 3). Error bars are SEM.
