Table 2.
Category | Classification | Description |
---|---|---|
Ia | Strong | Evidence from a meta-analysis of randomized, controlled trials |
Ib | Strong | Evidence from at least one randomized, controlled trial |
IIa | Less Strong | Evidence from at least one controlled study without randomization |
IIb | Less Strong | Evidence from at least one other type of quasi-experimental study |
III | Weaker | Evidence from descriptive studies, such as comparative studies, correlation studies, and case control studies |
IV | Weaker | Evidence from expert committee reports, opinions or clinical experience of respected authorities, or both |
Inconsistent | Evidence from small studies that are inconsistent in outcome | |
Speculative | Posited relationships are based essentially on extrapolation from mechanism |
Adapted from Manz 104