Table 3.

Changes in Immune Status from Baseline Values

	5–7 days post				6 months post				12 months post				60 months post
	Amalgam		Composite		Amalgam		Composite		Amalgam		Composite		Amalgam		Composite
Variable	N	Mean	N	Mean	N	Mean	N	Mean	N	Mean	N	Mean	N	Mean	N	Mean
Total WBC	23	−0 ±3.6	24	.4±7.2	24	0.6±3.5	29	0.7±3.8	17	1.2±5.8	21	−0.4±3.6	20	−1.0±4.0	23	−1.7±5.5
% Lymphocytes	22	1.5±10.7	24	.71±11.9	24	6.8±12.1	28	3.6±14.9	17	10.4±20.2	21	7.5±14.6	20	−5.1±8.5	23	−8.7±13.3
% Granulocyes	22	−1.6 ±11.1	24	−1.2±11.8	24	−6.7±2.5	28	−0.1±3.3	17	−9.9±20.6	21	−7.7±15.2	20	1.5±8.5	23	4.4±12.7
% Monocytes	22	−.0 ±1.3	24	.3±1.6	24	−0.2±2.0	28	0.1±1.3	17	−2.1±2.4	21	−1.4±1.4	20	−0.2±1.3	23	−0.8±1.8
T-cell function:
%CD69+ (ctrl)	23	−.2±3.8	24	−.0±2.4	24	0.6±2.9	29	2.5±4.2	17	1.3±3.6	21	0.6±2.8	20	1.7±5.5	23	7.2±19.5
%CD69+ (PHA)	23	−6.5±23.6	24	4.2±20.8	24	−1.5±26.3	28	4.5±20.6	17	5.7±9.6	21	5.5±28.4	20	0.9±17.0	23	4.0±17.9
%CD25+ (ctl)	23	.3±4.4	24	−.0±3.0	24	0.5±4.4	28	2.3±4.4	17	1.1±4.2	21	0.4±3.7	20	3.9±7.9	23	4.6±6.6
%CD25+ (PHA)	23	−6.0±25.3	24	1.3±28.1	24	2.0±31.4	28	4.7±36.3	17	13.8±18.6	21	13.6±30.7	20	14.8±16.3	23	14.0±24.4
B-cell function:
%CD69+ (ctl)	23	−.9±11.3	24	−2.5±10.4	24	2.9±14.2	28	4.0±16.2	17	2.1±10.8	21	−3.4±9.8	20	−3.8±22.0	23	−6.6±11.5
%CD69+ (PWM)	23	−5.2±16.8	24	−2.2±21.6	24	−0.4±24.9	28	5.2±21.9	17	−5.9±22.3	21	−1.3±26.9	20	−8.4±24.9	23	1.8±14.1
%CD23+ (ctl)	23	0.1±9.9	24	−1.2±8.9	24	3.0±10.8	28	6.5±16.3	17	2.5±14.5	21	−1.5±11.8	20	−1.6±14.3	23	−3.0±11.6
%CD23+ (PHA)	23	2.5±12.5	24	1.5±21.7	24	9.8±25.7	28	13.0±28.4	17	−1.3±27.7	21	3.8±30.7	20	−3.3±26.9	23	10.9±23.5
Monocyte function:
% Eth+(ctl)	23	0.7±4.6	24	0.9±4.9	24	1.0±5.5	27	1.1±5.2	17	0.4±6.1	21	1.4±5.2	20	1.7±5.7	22	2.1±4.3
% Eth+(PMA)	23	−7.8±26.4	24	5.7±19.6	24	−6.2±19.9	27	−4.9±30.1	17	−30.7±22.7	21	−18.4±26.1	20	6.3±21.1	22	3.1±26.8
% Rho+(ctl)	23	−.7±7.0	24	−2.3±11.0	24	−1.8±6.2	27	−2.8±11.3	17	−1.0±3.5	21	−0.4±3.5	20	−0.8±6.1	22	−2.3±11.4
% Rho+(PMA)	23	−8.4±30.2	24	0.4±29.2	24	−5.6±27.7	27	−2.1±29.7	17	−22±20.8	21	−15.3±26.7	20	7.8±24.5	22	8.8±28.7
Neutrophil function
% Eth+(ctl)	23	0.1±4.5	24	0.1±3.1	24	−0.6±3.8	28	0.3±5.5	17	−0.1±4.0	21	−0.9±5.4	20	−2.1±2.4	23	−0.4±6.5
% Eth+(PMA)	23	−6.5±20.4	24	3.1±21.1	24	−8.3±24.9	28	−9.8±34.6	17	−14.5±23.6	21	−13.4±36.6	20	2.3±8.1	23	6.1±19.6
% Rho+(ctl)	23	−.4±22.9	24	−.5±1.8	24	−3.8±17.1	28	0.3±4.2	17	0.1±3.5	21	0.6±4.2	20	−5.4±18.8	23	−1.2±3.2
% Rho+(PMA)	23	−8.0±19.5	24	7.2±24.5	24	−5.0±29.7	28	−0.5±26.3	17	−7.3±31.1	21	−2.0±25.4	20	1.8±13.0	23	9.3±25.4