Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1961 Nov;40(11):1997–2006. doi: 10.1172/JCI104426

STUDIES OF THE BLOOD-CEREBROSPINAL FLUID BARRIER TO CORTISOL IN THE DOG*

Nicholas P Christy 1,2, Robert A Fishman 1,2,
PMCID: PMC290904  PMID: 13879330

Full text

PDF
1997

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABELSON D., BARON D. N., TOAKLEY J. G. Studies of cerebrospinal fluid following oral administration of cortisone acetate or hydrocortisone. J Endocrinol. 1955 Mar;12(2):87–92. doi: 10.1677/joe.0.0120087. [DOI] [PubMed] [Google Scholar]
  2. BONDY P. K., SCHEUER J. The effect of intravenous cortisol injections on the plasma cortisol concentration in man. J Clin Invest. 1957 Jan;36(1 Pt 1):67–73. doi: 10.1172/JCI103411. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BUSH I. E. Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. Biochem J. 1952 Jan;50(3):370–378. doi: 10.1042/bj0500370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BUSH I. E., SANDBERG A. A. Adrenocortical hormones in human plasma. J Biol Chem. 1953 Dec;205(2):783–793. [PubMed] [Google Scholar]
  5. CHRISTY N. P., LONGSON D., HORWITZ W. A., KNIGHT M. M. Inhibitory effect of chlorpromazine upon the adrenal cortical response to insulin hypoglycemia in man. J Clin Invest. 1957 Apr;36(4):543–549. doi: 10.1172/JCI103452. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. CHRISTY N. P., WALLACE E. Z., GORDON W. E., JAILER J. W. On the rate of hydrocortisone clearance from plasma in pregnant women and in patients with Laennec's cirrhosis. J Clin Invest. 1959 Feb;38(2):299–305. doi: 10.1172/JCI103802. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. CRANNY R. L., KELLEY V. C. The use of hydrocortisone in the treatment of tuberculous meningitis; a study of steroid concentrations in cerebrospinal fluid. AMA J Dis Child. 1958 Aug;96(2):165–168. doi: 10.1001/archpedi.1958.02060060167006. [DOI] [PubMed] [Google Scholar]
  8. DAUGHADAY W. H. Binding of corticosteroids by plasma proteins. I. Dialysis equilibrium and renal clearance studies. J Clin Invest. 1956 Dec;35(12):1428–1433. doi: 10.1172/JCI103400. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. DAUGHADAY W. H. Binding of corticosteroids by plasma proteins. III. The binding of corticosteroid and related hormones by human plasma and plasma protein fractions as measured by equilibrium dialysis. J Clin Invest. 1958 Apr;37(4):511–518. doi: 10.1172/JCI103632. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. DAUGHADAY W. H. Binding of corticosteroids by plasma proteins. V. Corticosteroid-binding globulin activity in normal human beings and in certain disease states. AMA Arch Intern Med. 1958 Feb;101(2):286–290. doi: 10.1001/archinte.1958.00260140118017. [DOI] [PubMed] [Google Scholar]
  11. DE MOOR P., HENDRIKX A., HINNEKENS M. Extra-adrenal influence of corticotropin (ACTH) on cortisol metabolism. J Clin Endocrinol Metab. 1961 Jan;21:106–109. doi: 10.1210/jcem-21-1-106. [DOI] [PubMed] [Google Scholar]
  12. EIK-NES K., BRIZZEE K. R. Adrenocortical activity and metabolism of 17-hydroxycorticosteroids in thyroidectomized dogs. Am J Physiol. 1956 Feb;184(2):371–375. doi: 10.1152/ajplegacy.1956.184.2.371. [DOI] [PubMed] [Google Scholar]
  13. FISHMAN R. A. Exchange of albumin between plasma and cerebrospinal fluid. Am J Physiol. 1953 Oct;175(1):96–98. doi: 10.1152/ajplegacy.1953.175.1.96. [DOI] [PubMed] [Google Scholar]
  14. FISHMAN R. A. Factors influencing the exchange of sodium between plasma and cerebrospinal fluid. J Clin Invest. 1959 Oct;38:1698–1708. doi: 10.1172/JCI103948. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. FISHMAN R. A., RANSOHOFF J., OSSERMAN E. F. Factors influencing the concentration gradient of protein in cerebrospinal fluid. J Clin Invest. 1958 Oct;37(10):1419–1424. doi: 10.1172/JCI103732. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. FLORINI J. R., BUYSKE D. A. Plasma protein binding of triamcinolone-H3 and hydrocortisone-4-C14. J Biol Chem. 1961 Jan;236:247–251. [PubMed] [Google Scholar]
  17. FUKUSHIMA D. K., BRADLOW H. L., HELLMAN L., ZUMOFF B., GALLAGHER T. F. Metabolic transformation of hydrocortisone-4-C14 in normal men. J Biol Chem. 1960 Aug;235:2246–2252. [PubMed] [Google Scholar]
  18. GOLD N. I. Partial characterization of the metabolites of cortisol-4-C-14 in the dog. I. The intact dog. J Biol Chem. 1961 Jul;236:1924–1929. [PubMed] [Google Scholar]
  19. Gold N. I., Smith L. L., Moore F. D. CORTISOL METABOLISM IN MAN: OBSERVATIONS OF PATHWAYS, POOL SIZES OF METABOLITES AND RATES OF FORMATION OF METABOLITES. J Clin Invest. 1959 Dec;38(12):2238–2252. doi: 10.1172/JCI104005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. HELLMAN L., BRADLOW H. L., ADESMAN J., FUKUSHIMA D. K., KULP J. L., GALLAGHER J. F. The fate of hydrocortisone-4-C14 in man. J Clin Invest. 1954 Aug;33(8):1106–1115. doi: 10.1172/JCI102984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. KUIPERS F., ELY R. S., KELLEY V. C. Metabolism of steroids: the removal of exogenous 17-hydroxycorticosterone from the peripheral circulation in dogs. Endocrinology. 1958 Jan;62(1):64–74. doi: 10.1210/endo-62-1-64. [DOI] [PubMed] [Google Scholar]
  22. LIEBERMAN S., TEICH S. Recent trends in the biochemistry of the steroid hormones. Pharmacol Rev. 1953 Sep;5(3):285–380. [PubMed] [Google Scholar]
  23. PETERSON R. E., NOKES G., CHEN P. S., Jr, BLACK R. L. Estrogens and adrenocortical function in man. J Clin Endocrinol Metab. 1960 Apr;20:495–514. doi: 10.1210/jcem-20-4-495. [DOI] [PubMed] [Google Scholar]
  24. PETERSON R. E., WYNGAARDEN J. B., GUERRA S. L., BRODIE B. B., BUNIM J. J. The physiological disposition and metabolic fate of hydrocortisone in man. J Clin Invest. 1955 Dec;34(12):1779–1794. doi: 10.1172/JCI103233. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. RALL D. P., STABENAU J. R., ZUBROD C. G. Distribution of drugs between blood and cerebrospinal fluid: general methodology and effect of pH gradients. J Pharmacol Exp Ther. 1959 Mar;125(3):185–193. [PubMed] [Google Scholar]
  26. ROMANOFF E. B., HUDSON P., PINCUS G. Isolation of hydrocortisone and corticosterone from human adrenal vein blood. J Clin Endocrinol Metab. 1953 Dec;13(12):1546–1548. doi: 10.1210/jcem-13-12-1546. [DOI] [PubMed] [Google Scholar]
  27. SANDBERG A. A., EIK-NES K., NELSON D. H., TYLER F. H. Levels of 17-hydroxycorticosteroids in body fluids. J Lab Clin Med. 1954 Jun;43(6):874–879. [PubMed] [Google Scholar]
  28. SILBER R. H., PORTER C. C. The determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma. J Biol Chem. 1954 Oct;210(2):923–932. [PubMed] [Google Scholar]
  29. SLAUNWHITE W. R., Jr, SANDBERG A. A. Transcortin: a corticosteroid-binding protein of plasma. J Clin Invest. 1959 Feb;38(2):384–391. doi: 10.1172/JCI103812. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. UPTON G. V., BONDY P. K. The binding of cortisol by plasma protein. Arch Biochem Biophys. 1958 Nov;78(1):197–205. doi: 10.1016/0003-9861(58)90328-x. [DOI] [PubMed] [Google Scholar]
  31. WOODBURY D. M. Relation between the adrenal cortex and the central nervous system. Pharmacol Rev. 1958 Jun;10(2):275–357. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES