Table 3.

10-year mathematics SNP and SNP-set associations with reading and general cognitive ability.

	g at 10		Teacher reading at 10		Web reading at 10
	Cor	N	Cor	N	Cor	N
rs11225308	0.056*	1661	0.056**	1819	0.042*	1858
rs363449	0.032	1645	0.071**	1827	0.047*	1845
rs17278234	0.023	1650	0.033	1830	0.060**	1850
10-SNP set	0.121**	1431	0.118**	1576	0.110**	1609
43-SNP set	0.107**	1436	0.137**	1578	0.101**	1613
rp	0.596**	1762	0.673**	1971	0.517**	1953

Association was assessed with rs11225308, rs363449, rs17278234, and the 10- and 43-SNP sets previously associated with mathematics at age 10. Associations are presented as correlations between the quantitative traits and additive genotypic values (as 0, 1, and 2 'increasing' alleles) for SNPs and additive SNP scores for SNP sets. G at 10 = general cognitive ability at age 10; Teacher reading at 10 = NC-based teacher-ratings of reading ability at age 10; Web reading at 10 = performance on web-administered tests of reading at age 10; Cor = Pearson product moment correlations (p-values in italics); N = size of sample analysed; r_p = phenotypic correlation with mathematic composite score at age 10. One-tailed p-values were generated for all SNP-associations. * = nominally significant associations (p < 0.05). ** = associations withstanding Bonferroni testing for the five (three individual SNP and two SNP-set) association tests conducted simultaneously for each measure (p < 0.01).