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. Author manuscript; available in PMC: 2010 Jul 23.
Published in final edited form as: J Neurophysiol. 2003 Jan 2;89(4):1929–1940. doi: 10.1152/jn.00780.2002

TABLE 3.

Weighted decay τw of mIPSCs analyzed before and after bath application of the non-α4 selective BDZ agonist LZM (10 µM) or the α4 selective BDZ agonist RO15-4513 (10 µM) to hippocampal slices from control or 48 h 3α,5β-THP-treated female rats

Pre-drug τw, ms Post-drug τw, ms
Control
   LZM 11.2 ± 3.0 22.4 ± 1.30*
   RO 15-4513 11.2 ± 3.0 8.7 ± 0.6*
48 h
   3α,5β-THP
   LZM 8.79 ± 1.2 13.1 ± 0.9*
   RO 15-4513 8.79 ± 1.2 20.3 ± 3.3*

All recordings were carried out at 27°C. Values were averaged from individual cell means for each condition (n = 2,000 mIPSCs, 15–25 cells/group, 6–15 rats/group). τw, time constants; LZM, lorazepam.

*

P < 0.05 vs. control values.