Table 2.
Results of Cox Regression Analysis.
| Factor | Hazard Ratio | 95% CI | p |
|---|---|---|---|
| Islet TNFα | 0.995* | 0.989 to 1.000 | 0.048† |
| Stromal TNFα | 1.006* | 1.002 to 1.011 | 0.007† |
| Age | 1.022 | 1.000 to 1.043 | 0.049† |
| Pathological stage | 0.002† | ||
| I | 1.000 | ||
| II | 0.283‡ | 0.077 to 1.035 | 0.056 |
| IIIa | 0.373 | 0.102 to 1.372 | 0.138 |
| IIIb and IV | 0.712 | 0.194 to 2.619 | 0.609 |
| Grade - differentiated | 0.078† | ||
| Well | 1.000 | ||
| Moderate | 0.481§ | 0.177 to 1.306 | 0.151 |
| Poor | 0.752 | 0.488 to 1.159 | 0.197 |
| Histology | 0.711 | ||
| Squamous | 1.000 | ||
| Adenocarcinoma | 0.708 | 0.323 to 1.553 | 0.389 |
| Large | 0.828 | 0.363 to 1.891 | 0.654 |
| Other NSCLC | 0.621 | 0.235 to 1.640 | 0.336 |
*Continuous variable used. For every increase of 1 in the value of the variable, the hazard increases by the value of the hazard ratio.
† Overall significance as a prognostic factor
‡ Hazard relative to stage I
§ Hazard relative to well differentiated
¶ Hazard relative to squamous