Table 1.
Flux and metabolite abbreviations in the fumarase MCS network. Suffixes “_c” and “_m” are added in the network diagram to denote cytoplasmic and mitochondrial compartments, respectively.
| Flux abbreviation | Name | Met abbreviation | Met name |
|---|---|---|---|
| 3SALAASPm | Cysteinesulfinate-aspartate mitochondrial shuttle | 3sala | 3-Sulfino-L-alanine |
| 3SALATAim | 3-sulfino-alanine transaminase (irreversible), mitochondrial | 3snpyr | 3-Sulfinopyruvate |
| 3SPYRSPm | 3-sulfinopyruvate hydrolase (spontaneous reaction), mitochondrial | adp | ADP |
| ASNNm | L-asparaginase (mitochondrial) | akg | 2-Oxoglutarate |
| ASNtm | L-asparagine transport, mitochondrial | asn-L | L-Asparagine |
| ASPGLUm | Aspartate-glutamate mitochondrial shuttle | asp-L | L-Aspartate |
| ASPTAm | Aspartate transaminase | atp | ATP |
| CYANSTm | Cyanide sulfurtransferase, mitochondrial | cyan | Hydrogen cyanide |
| CYANt | Cyanide transport via diffusion (extracellular to cytosol) | cys-L | L-Cysteine |
| CYANtm | Cyanide transport via diffusion (mitochondrial) | ficytC | Ferricytochrome c |
| CYOOm3 | Cytochrome c oxidase, mitochondrial complex IV | focytC | Ferrocytochrome C |
| CYSO | Cysteine oxidase | fum | Fumarate |
| FUMm | Fumarase, mitochondrial | glu-L | L-Glutamate |
| FUMSO3tm | Fumarate:sulfite antiport, mitochondrial | h2o2 | Hydrogen peroxide |
| FUMSO4tm | Fumarate:sulfate antiport, mitochondrial | hco3 | Bicarbonate |
| FUMtm | Fumarate transport, mitochondrial | mal-L | L-Malate |
| FUMTSULtm | Fumarate:thiosulfate antiport, mitochondrial | nh4 | Ammonium |
| MALSO3tm | Malate:sulfite antiport, mitochondrial | o2 | O2 |
| MALSO4tm | Malate:sulfate antiport, mitochondrial | o2s | Superoxide anion |
| MALTSULtm | Malate:thiosulfate antiport, mitochondrial | oaa | Oxaloacetate |
| MDHm | Malate dehydrogenase, mitochondrial | pyr | Pyruvate |
| O2Stm | Superoxide anion transport via diffusion (mitochondria) | so3 | Sulfite |
| PCm | Pyruvate carboxylase | so4 | Sulfate |
| SPODMm | Superoxide dismutase | succ | Succinate |
| SUCDlm | Succinate dehydrogenase | tcynt | Thiocyanate |
| SULFOX | Sulfite oxidase | tsul | Thiosulfate |
| TCYNTt | Thiocyanate transport via diffusion (cytosol to extracellular) | ||
| TCYNTtm | Thiocyanate transport via diffusion (mitochondrial) | ||
| TSULt4_3 | Thiosulfate transport via sodium symport |