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Class R inhibitor-1 (INH-1) completely, and class B INH-18 partially, restore resting B cell immunoglobulin (Ig)M+IgD+ phenotype in Murphy Roths large (MRL)-Faslpr/lpr mice. CD40+CD19+ gated splenic B cells were analysed for IgM and IgD expression in phosphate-buffered saline (PBS) or inhibitory oligonucleotide (INH-ODN)-treated MRL-Faslpr/lpr mice.
