Table 3.

Classification of inhibitory oligonucleotides.

Class	Distinguishing feature	Example	TLR-9 inhibition in B cells	TLR-9 inhibition in DC	TLR-7 inhibition (backbone effect)	Effect in lupus	Reference
G	G4-stacking	A151	+	+++	++	++	[137]
R	Palindromic	INH-1	+	+++	++	++	[150]
B	Linear	INH-18	+++	+++	++	−/+	[150]

TLR, Toll-like receptor.